Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical Trials
Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical Trials
he FAIR data guiding principles have been recently developed and widely adopted to improve the Findability, Accessibility, Interoperability, and Reuse of digital assets in the face of an exponential increase of data volume and complexity. The FAIR data principles have been formulated on a general level and the technological implementation of these principles remains up to the industries and organizations working on maximizing the value of their data. Here, we describe the data management and curation methodologies and best practices developed for FAIRification of clinical exploratory biomarker data collected from over 250 clinical studies. We discuss the data curation effort involved, the resulting output, and the business and scientific impact of our work. Finally, we propose prospective planning for FAIR data to optimize data management efforts and maximize data value.
he FAIR data guiding principles have been recently developed and widely adopted to improve the Findability, Accessibility, Interoperability, and Reuse of digital assets in the face of an exponential increase of data volume and complexity. The FAIR data principles have been formulated on a general level and the technological implementation of these principles remains up to the industries and organizations working on maximizing the value of their data. Here, we describe the data management and curation methodologies and best practices developed for FAIRification of clinical exploratory biomarker data collected from over 250 clinical studies. We discuss the data curation effort involved, the resulting output, and the business and scientific impact of our work. Finally, we propose prospective planning for FAIR data to optimize data management efforts and maximize data value.
Staton, Tracy、Chen, Cong、Ferguson, Rebecca、Adam, Laura、Wong, Jee-Yeon、Arefolov, Alexander、Kanigel, Kimberly、Tajhya, Rajeev、Farhy, Chen、Budovskaya, Yelena、Das, Diya、Whitley, Maryann、Huang, Hongmei、Polesskaya, Oksana、Zeng, Xiangpei、Brown, Shoshana、Lu, Christina、McCreary, Mark
医学研究方法生物科学研究方法、生物科学研究技术
ata managementData curationClinical studiesFAIR dataBiomarkersData modelMetadataData standardsData governance
Staton, Tracy,Chen, Cong,Ferguson, Rebecca,Adam, Laura,Wong, Jee-Yeon,Arefolov, Alexander,Kanigel, Kimberly,Tajhya, Rajeev,Farhy, Chen,Budovskaya, Yelena,Das, Diya,Whitley, Maryann,Huang, Hongmei,Polesskaya, Oksana,Zeng, Xiangpei,Brown, Shoshana,Lu, Christina,McCreary, Mark.Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical Trials[EB/OL].(2022-11-18)[2025-05-23].https://chinaxiv.org/abs/202211.00203.点此复制
评论