氟化物接枝聚合物刷修饰的抗蛋白吸附和抗细菌黏附表面

In this paper,the hydrophilic PHEAA brush is grafted to silicon surface, followed by the decoration of -C3F7 with lower surface energy to the side chains in PHEAA brushes. The method of polymerization prior to decoration is easy to operate and has more option in monomers to polymerize. The surface modified with functional materials by this means is long-lasting and stable. The amount of Fg adsorbed on the modified surface by BCA. It turns out that hydrophilic PHEAA brush is repellant to Fg adsorption, after the decoration of -C3F7 to obtain the amphiphilic polymer-grafted surface with enhanced resistance to Fg adsorption. The attachment of Actinomyces naeslundii and Streptococcus mutans on the modified surfaces is observed by SEM and fluorecent microscopy after incubation for 4 h or 24 h. The experiment results show that Si-PHEAA can resist adhesion of Actinomyces naeslundii and Streptococcus mutans, Si-PHEAA-C3F7 has better property of resistance to Actinomyces naeslundii and Streptococcus mutans adhesion, which has potential durability.