通过LC-MS/MS利用分子印迹聚合物对三丁基锡进行检测

here is a high interest in speciation of tributyltinchloride(TBT) in environment samples, such as seawater, due to the influence in the transmission of the contamination in the trophic chain. The environmental impact of organotin compounds has given particulate importance to analytical studies. This paper reports that applying a molecular imprinting technolgy with liquid chromatography-tandem mass spectrometry (LC-MS/MS) to this field. The imprinted polymer has been synthesised by the non-covalent free redical approach using acrylamide(AM) as monomer in the presence of TBT as template molecule in acetonitrile solvent. The ability of the polymer synthesised to retain and distinguish TBT has been evaluated and optimized. The analytical characteristics included linearity（10-100000μgL-1）, a pre-concentration factor of 100, and detection limit of 0.01 μgl-1.