团体心理干预对胃癌患者焦虑、血浆皮质醇和睡眠质量的影响
目的 探索团体心理干预对胃癌患者血浆皮质醇、焦虑和睡眠质量的影响。方法 采用完全随机对照设计，将已确诊为胃癌且已完成临床治疗的78名患者，分为团体心理干预组（n=39）和空白对照组（n=39）。对干预组进行每周1次，每次90 min，共8 周的团体心理干预，同时对照组不接受任何形式的心理干预。采用焦虑自评量表（SAS）、血浆皮质醇浓度和阿森斯（AIS）睡眠自评量表分别对两组患者进行干预前和干预结束当周进行评估。结果 8周干预结束时，干预组脱落病号3人，对照组脱落病号5人。干预前两组患者焦虑（SAS）得分无显著性差异（t=1.31，P>0.05），血浆皮质醇浓度无显著性差异（t=0.65，P>0.05），两组患者睡眠质量评分（AIS）无显著差异（t=0.84，P>0.05）。经团体心理干预后，干预组患者焦虑（SAS）评分显著低于对照组（t=-2.72，P<0.01），血浆皮质醇浓度显著低于对照（t=-2.44，P<0.05），AIS评分显著低于对照组（t=-3.00，P<0.01）。结论 对胃癌患者进行团体心理干预能显著改善患者的焦虑程度，降低血浆皮质醇浓度，减少身体不良应激，改善睡眠质量，提高患者的生存质量，值得运用和推广。
Objective To explore the effect of group psychological therapy on anxiety and Cortisol and Sleep in gastric cancerpatients. Methods Totally 78 patients previously diagnosed with gastric cancer, and finished active treatment, were equallyrandomized into observation group and control group. 39 patients joined the intervention group, which consisted of 8consecutive, weekly sessions of 90 minutes each in length, whereas another 39 served as control subjects without receiving anypsychological interventions during this study. All participants completed baseline measures and post-intervention measures(8weeks later or after 8 times interventions) by Self-Rating Anxiety Scale (SAS), and Cortisol and AIS . Results there are nosignificant differencesP>0.05between this two groups patients on SAS and Cortisol and AIS before the treatment. After thetreatment, anxiety(t=-2.72, P<0.01) and Cortisol-2.44, P<0.05and AISt=-3.00, P<0.01) of patients were all decreased. SAS andCortisol and VAS level in both groups had significant differences. Conclusion This study provides evidence for the positiveeffect of group psychological therapy for gastric cancer patients on SAS, Cortisol and sleep.
吴 宁；吉洪标；余书勇；陈运雅
肿瘤学临床医学
胃癌团体心理干预血浆皮质醇焦虑睡眠
吴 宁；吉洪标；余书勇；陈运雅.团体心理干预对胃癌患者焦虑、血浆皮质醇和睡眠质量的影响[EB/OL].(2017-12-07)[2025-08-02].https://chinaxiv.org/abs/201712.00504.点此复制
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