模拟微重力下Notch信号通路对神经干细胞分化的影响

Notch signaling pathway is an inhibitory signaling pathway, which is generally considered to play a role by \"lateral inhibition mechanism\". Researches show that the Notch signaling pathway has important implications on the proliferation and differentiation of neural stem cells. Furthermore with the development of space life sciences, the effect of the space environment on the human central nervous system has drawn people\'s attention. The effect of microgravity condition on the differentiation of neural stem cells has gradually become a research hotspot. Combine the function of Notch signaling pathway in the differentiation of neural stem cells with the situation of the differentiation of neural stem cells under simulated microgravity, the possible impact of Notch signaling pathway on the differentiation of neural stem cells under microgravity condition has been discussed in this paper.