植物病原真菌入侵寄主需要CDC10基因的参与

Rice blast and grey mould are two damaging fungal plant diseases, which are induced by Magnaporthe oryzae and Botrytis cinerea, respectively. The rice blast fungus penetrates into host cells by appressorium with enormous turgor pressure, however, Botrytis cinerea forms appressorium-like structures or infectious cushions for infection. In this paper, we found that CDC10, a protein involved in cell division control, play important conserved roles in formation of infectious structures, in fungal plant pathogens. For Magnaporthe oryzae, cdc10 mutants lost ability to penetrate, due to failure of appressorium formation as discovered by microscopic observation. The pathogenicity could be rescued by recover of the native CDC10 gene. Same results were also observed in Botrytis cinerea, and the knock-out cdc10 mutants could not infect host successfully either. Our data indicated that phytopathogenic fungi use conserved CDC10 to penetrate into host.