成人女性寰椎朗格汉斯细胞增多症一例及文献复习

26-year-old woman complained of headache for ten years, with aggravation for 3 months. No neurological deficits were observed. Physical examination demonstrated obvious restriction of the neck motion. CT examination confirmed a sharply osteolytic lesion of the right posterior lacerate foramen area, after enhancement, the tumor mass density overall increased obviously, but not very uniform. On MRI, the soft-tissue mass is isointense on T1, but it enhances homogeneously after contrast administration. Based on the described radiological features of the bone deficit, an initial diagnosis of langerhans' cell histocytosis was proposed. Under general anaesthesia a grey-red tumor of approximately 3.5 × 5.5 × 6 cm was completely removed from the atlas. Tumor had a tough texture with clear border and abundant blood supply. Histopathologically, it was proved to be langerhans' cell histocytosis.