80例中晚期胃癌患者凝血指标及血瘀症状的临床分析
linical Analysis on the Coagulation Indicators and Blood Stasis Symptoms in 80 patients with advanced Gastric Cancer
目的 客观评价中晚期胃癌患者凝血指标的改变与中医证候血瘀证临床症状评分的相关性。方法 回顾性分析80例中晚期胃癌患者的凝血指标，主要包括凝血酶原时间（PT）、活化部分凝血酶原时间（APTT）、纤维蛋白原含量（FIB）、凝血酶凝结时间（TT）、D-二聚体（DD），与正常健康人的凝血指标标准均值相比较进行统计学分析；参照血瘀证临床症状评分标准，对患者症状体征进行分级、评分。结果 中晚期胃癌患者凝血指标中FIB、DD异常升高所占比例最多，P<0.05，差异有统计学意义；63.7%的患者中医辩证属于血瘀证，且与凝血指标异常存在相关性，P<0.05，有统计学意义。结论 多数中晚期胃癌患者存在凝血指标异常及中医血瘀证症状，且两者有相关性。
Object To Objectively appraise the correlativity of the coagulation indicators changes with clinical symptom scores of the blood stasis in patients with advanced gastric cancer. Methods The levels of PT, APTT, Fib, TT, D-dimer compared with the standard mean were analyzed according to retrospective investigation, referring to the clinical grading standard of blood stasis symptoms, patients' blood stasis signs and symptoms were graded. Results The levers of Fib, D- dimer of patients with advanced gastric cancer were increased obviously (P<0.05), the patients with blood stasis symptoms is accounted for 63.7%,and logistic regression analysis shows there is strong correlation between blood stasis symptoms and coagulation indicator changes(P<0.05).Conclusion Most patients with advanced gastric cancer have coagulation indicator changes and blood stasis symptoms, and there is correlation between them.
郭晓青、陈信义、田劭丹、刘庆、侯丽
肿瘤学中医学临床医学
中晚期胃癌凝血指标血瘀证
advanced gastric cancercoagulation indicatorblood stasis symptoms
郭晓青,陈信义,田劭丹,刘庆,侯丽.80例中晚期胃癌患者凝血指标及血瘀症状的临床分析[EB/OL].(2013-06-06)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/201306-73.点此复制
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