病原菌群体感应机制及应用

Bacteria secret and sense the small signals corresponding to the density of their population and then for them gene expression which is called bacterial quorum－sensing. Studies show that many kinds of pathogenic take good advantage of quorum sensing to manage their infection, the virulence gene’s expression and the final step of infection. Therefore, interference and break the bacterial quorum－sensing could effectively weaken the pathogenic of the bacteria and make good sense of new therapeutic strategies.