G6PD缺乏症发病的分子病理学新机制

Gluocose-6-phosphate dehydrogenase （G6PD） deficiency is the most common enzymopathies, affecting about 400 million people worldwide. G6PD deficiency is caused mostly by mutations in the G6PD gene, however, the classical pathogenesis can't give definite explanations between the relationship of phenotype and genotype to a minority of cases. In recent years, some new mechanisms in the molecular pathology on G6PD deficiency were found. To know better about this disease, the new mechanisms in the molecular pathology on G6PD deficiency is reviewed.