组蛋白修饰与DNA及microRNA甲基化在胃癌中的研究进展
dvances in Study on Histone Modification and Methylation of DNA and microRNA in Gastric Cancer
表遗传学修饰在胃癌的发生、发展中起重要作用,组蛋白修饰与DNA甲基化及microRNA甲基化作为表遗传学的重要组成部分已成为研究的热点.大量研究发现蛋白修饰与DNA甲基化及microRNA甲基化在胃癌中分别发生了不同程度的改变， 这种变化具有重要的临床价值，可能成为判断肿瘤生物学特性及临床预后的重要指标之一。本文就与胃癌相关的组蛋白修饰与DNA甲基化及microRNA甲基化研究进展作一综述.?????
Histone modification and methylation of DNA and microRNA, as important components of epigenetics that plays vital role in the development and progress of gastric cancer, has become a research hotspot. Accumulating studies have demonstrated that changes in Histone modification and methylation of DNA and microRNA occurred in gastric cancer, having significant value in clinical practice and May become the judge one of the important indexes of tumor biological characteristics and clinical outcome.This article reviewed the recent advances in study on Histone modification and methylation of DNA and microRNA in gastric cancer.?????
戴冬秋、刘剑
肿瘤学基础医学遗传学
胃癌NA甲基化组蛋白修饰microRNA甲基化
gastric cancerHistone ModificationDNA MethylationmicroRNA Methylation
戴冬秋,刘剑.组蛋白修饰与DNA及microRNA甲基化在胃癌中的研究进展[EB/OL].(2014-01-09)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201401-431.点此复制
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