基于光纤光栅分布式温度传感器的激光诱导间质热疗活体实验

In this paper, we measured the temperature distribution of liver tissue both in vivo and in vitro during Laser Induced Interstitial Thermotherapy (LITT). Fiber Bragg grating (FBG) was embedded in the laser irradiated bio tissues used as fully distributed temperature sensor. The temperature profile was reconstructed from its reflection spectra. The temperature measurement system we built can measure the FBG axial temperature distribution. We studied the dependence of the temperature distribution and laser output power experimentally and compared the results of in vivo and in vitro under similar laser irradiating conditions. Experimental results show that the slope and trend of the measured temperature curves in vivo and in vitro are almost identical. Due to influence of body temperature, the in vivo measured temperature is higher than the in vitro one with an almost constant temperature difference value.