Monoallelic methylation and allele specific expression in a social insect
Monoallelic methylation and allele specific expression in a social insect
Abstract Social insects are emerging models for epigenetics. Here we examine a link between monoallelic methylation and monoallelic expression in the bumblebee Bombus terrestris using whole methy-lome and transcriptome analysis. In mammals and flowering plants, genomic imprinting (parent of origin allele specific expression) often involves monoallelic expression and methylation. We found nineteen genes displaying monoallelic methylation and expression. They were enriched for functions to do with social organisation in the social insects. Evolutionary theory predicts that social organisation in the hymenoptera invovles genomic imprinting.
Lee Kate D.、Amarasinghe Harindra E.、Mallon Eamonn B.、Lonsdale Zo? N.、Nathanael Despina、Kyriakidou Maria
Bioinformatics and Biostatistics Support Hub (B/BASH), University of LeicesterDepartment of Genetics, University of LeicesterDepartment of Genetics, University of LeicesterDepartment of Genetics, University of LeicesterDepartment of Genetics, University of LeicesterDepartment of Genetics, University of Leicester
遗传学分子生物学昆虫学
Lee Kate D.,Amarasinghe Harindra E.,Mallon Eamonn B.,Lonsdale Zo? N.,Nathanael Despina,Kyriakidou Maria.Monoallelic methylation and allele specific expression in a social insect[EB/OL].(2025-03-28)[2025-08-02].https://www.biorxiv.org/content/10.1101/022657.点此复制
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