三七内生真菌Preussia isomera 次级代谢产物的分离鉴定
Isolation and identification of secondary metabolites from Preussia isomera, isolated from Panax notoginseng
目的研究三七内生真菌Preussia isomera次级代谢产物，对Preussia isomera规模发酵产物的乙酸乙酯部分进行分离纯化，结构鉴定。方法利用硅胶柱层析，葡聚糖凝胶柱层析，薄层层析半制备液相等手段进行分离纯化，利用核磁进行结构鉴定。结果从Preussia isomera发酵产物中分离得到6个化合物。结论6个化合物分别被鉴定为5(hydroxymethyl)furan-3-carboxylicacid (1)，orsellinic acid (2)，methyl orsellinate (3)，lecanoric acid (4)，brocaenol A (5)，aflatoxinB1 (6)。6个化合物均为首次从该真菌中报道。
im: To study the secondary metabolite of endogenous fungus Preussia isomera, isolated from panax notoensis. Methods: Various chromatographic techniques, such as HPLC, TLC, Sephadex LH-20 and so on, were used for separation and purification. Results: Six compounds were isolated from the Preussia isomera. Conclusion: Their structures were identified 5(hydroxymethyl)furan-3-carboxylicacid (1)，orsellinic acid (2)，methyl orsellinate (3)，lecanoric acid (4)，brocaenol A (5)，aflatoxin B1 (6).
杨小龙、徐露琳
微生物学生物化学药学
天然药物化学植物内生真菌次级代谢产物分离鉴定
Natural medicinal chemistryEndophytic fungiSecondary metabolitesIsolation and identification
杨小龙,徐露琳.三七内生真菌Preussia isomera 次级代谢产物的分离鉴定[EB/OL].(2019-04-01)[2025-08-05].http://www.paper.edu.cn/releasepaper/content/201904-2.点此复制
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