超临界流体沉淀技术及其在药物制剂中的应用

Supercritical fluid precipitation technology becomes a widely application prospect the superfine particle preparation method by its unique merit. This article briefly summarized the SFP technology principle, the characteristic and the related application of rapid expansion of supercritical solution process, gas anti-solvent process, supercritical anti-solvent process, aerosol solvent extraction system, solution enhanced dispersion by supercritical fluid technology, and precipitation from gas saturated solution.