Z形SG人工血管体外疲劳实验研究
he study on the in vitro fatigue property of the stent-graft supported with zigzag shaped stents
腔内隔绝术用人工血管(Stent-graft,SG)是治疗腹主动脉瘤的关键装置,它主要用于将动脉瘤隔绝与正常血流之外,以避免瘤体的破裂。目前,带有"Z"字形状的金属支架的SG(简称:Z形SG)在临床上最为广泛使用。但据报道,一些Z形SG在移植后出现了不同程度的疲劳。因此,有必要在体外模拟环境中探究Z形SG的疲劳特性。本文旨在通过SG的扭转弯折疲劳模拟装置提供一个体外动态仿真模拟环境,测试评估Z形SG的体外疲劳性能。结果表明,两个Z形SG试样在分别进行8小时和7小时的扭转弯折加速疲劳实验后,织物覆膜出现破洞,缝合线发生断裂并且支架上出现了划痕。推测这主要是由Z形支架的尖端和缝合线的缝合张力过大导致了SG的失效破损。此外,镍钛金属支架上的划痕可能破坏了TiO2(2上标,但格式无法修改)的表层并暴露出里层的有毒镍离子。因此,针对SG支架的结构设计,还有很多工作有待于进一步改善。
he stent-graft (SG) is the key device to treat AAAs with the effective method of Transluminally Placed Endovascular Grafts. It is used to isolate the aneurysm from the blood flow in case of its rupture. Presently, The stent-graft supported with zigzag shaped stents are widely used in clinical. But it has been reported that some devices presented different fatigue problems during explanations. Thus, it is necessary to investigate the fatigue properties of zigzag shaped stent-grafts in vitro under the simulation condition. This paper is to test and appraise the fatigue property of stent-graft supported with zigzag shaped stents with the in vitro SG fatigue simulation instrument with twist and buckling motion under a dynamic environment. The result showed that two stent-grafts supported with zigzag shaped stents presented the broken grafts and sutures and the scratched stents after 8 and 7 hours respectively. It was speculated that the failure of stent-grafts mainly casused by the sharp tip of zigzag shaped stents and the tightly stitching tension of sutures. Furthermore, TiO2 (2上标,格式无法修改) on the top layer might be destoryed and then the Nickel ions in the inner toxic layer would be exposed if the Nitinol stents were scratched by high-strength sutures. Thus, the structure's design of stents of stent-grafts supported with zigzag shaped stents should be inproved and stengthened.
杜佳、王璐、林婧、Robert Guidoin
医学研究方法基础医学外科学
疲劳特性扭转弯折SG体外模拟试验
fatigue propertiestwist and bucklingstent-graftin vitro simulated experiment
杜佳,王璐,林婧,Robert Guidoin.Z形SG人工血管体外疲劳实验研究[EB/OL].(2013-12-13)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201312-358.点此复制
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