香菇多糖硫酸酯层层自组装修饰的壳聚糖抗菌生物材料

In this work, the chitosan surfaces were modified by layer-by-layer self-assembly technique. Negatively charged lentinan sulfate and positively charged chitosan were alternately deposited onto the cross-linked chitosan substrate, in order to improve the surface property of the modified chitosan. The surface properties were measured by FTIR, water contact angle, and antibacterial bioactivity test. The results indicate that the modified chitosan surfaces become more hydrophilic, and have significant antibacterial bioactivity after layer-by-layer self-assembly modification.