从气虚血瘀论治难治性免疫性血小板减少性紫癜

Immune thrombocytopenic purpura(ITP) is an autoimmune disorder characterized by a low platelet count and mucocutaneous bleeding. Patients are considered to have refractory ITP(RITP) when they require treatment following failure to respond to initial treatment with glucocorticoids and also to splenectomy. The percentage of patients defined as having RITP varies from 11% to 35%.There has a difficult in treating RITP. Through clinical practice we found that Qi deficiency and blood stasis play an important role in occurrence, transform of pathogenesis and clinical expression of RITP.The treatment of RITP with Traditional Chinese Medicine(TCM) and integrated traditional and western medicine characterized by improve symptom obviously,good curative effect and little side effect et al.There has a practical meaning to found a improve clinical curative effect methods of treatment RITP and carry out research on mechanisms of the treatment of RITP with TCM. Invigorating Qi and dissipate stagnation and promoting blood circulation to remove blood stasis was formulated according to etiology and pathogenesis of RITP and relationship with clinical expression.It was used in clinical treatment and gained good effect.