去氢骆驼蓬碱衍生物对金黄色葡萄球菌感染小鼠作用研究

Objective: To determine the protective effect of harmine derivatives on Staphylococcus aureus infection in mice. Methods: Mice were infected with Staphylococcus aureus bacteria abdominal cause staph infections in animal models to understand the protective effect of oral administration of harmine derivatives of different doses of animal models. Results: The positive drug levofloxacin group of animals survival rate was 90%, Harmine animals survival rate was 50%, harmine derivatives low-dose group was 30% survival rate of animals, harmine derivatives animal survival dose group was 70%, harmine derivatives high dose animal survival rate was 80%. Conclusion: harmine derivatives than Harmine mice infected with Staphylococcus aureus is more protective effect against infection, and the protective effect against infections in the levofloxacin fairly.