羧酸甜菜碱酯的合成及其水解条件优化

hydrolysable cationic carboxybetaine ester (CBMA-1C2) is synthesized and used to optimize its hydrolysis process. The 1H NMR is used to calculate the degree of hydrolysis (DH) for terminal carboxybetain ester bond. The results show that when the concentration of sodium hydroxide , the hydrolysis time and hydrolysis temperature is 0.2mol/L, 1h and 37 ℃, respectively, DH of terminal carboxybetaine ester bond can reach 88~95% and the ester bond of methalcrylate does not be affected. If the CBMA-1C2 is hydrolyzed in ammonium water, the good relationship between DH of terminal carboxybetaine ester and concentration of ammonium water can be obtained, which provides the new possibilities for design and fabricate the hydrolysis controllable polymer brushes with antebacterial and antifouling properties simultaneously.