SUMO化分子与肿瘤关系的研究进展

SUMO was a classical ubiquitin pathway, which plays an important role in protein modification. Researchers found that SUMO molecules is overexpressed in many human cancers and SUMO molecules is pivotal in tumorigenesis and tumor development, it also affect the prognosis of cancer patients, which implies that SUMO molecules may be a target for tumor therapy. This paper focuses on the relationship of SUMO molecules with tumorigenesis and tumor development, and explores the possibility of becoming a target for tumor therapy.