光动力-光热联合治疗的光敏剂分子设计合成与性能研究

photosensitizer molecules for photodynamic-photothermal combined therapy have made significant progress in research, but there are still deficiencies in the treatment of cancer. If photodynamic therapy and photothermal therapy can be combined, it can not only overcome the limitations of PDT, but also seek a major breakthrough in the effect of cancer treatment. However, the traditional combined treatment process requires a long light time, which makes it difficult for patients to recover after surgery. For the purpose of simplifying treatment, scientists hope to design a photosensitizer with PDT/PTT effect. In this paper, by designing a new cyanine dye molecule-IR805, compared with ICG, it has better thermal stability under near-infrared long irradiation. and light-to-heat conversion capability.