猪肌肉PGC-1α与肌纤维类型转化的关系

We detected PGC-1α (PPARγ coactivator 1 alpha) mRNA expression as well as myofiber type composition in longissimus dorsi and semitendinosus muscle in Erhualian and Pietain to reveal the relationship of PGC-1α and myofiber type composition. Results shown that in longissimus dorsi, there were no significant differences of PGC-1α mRNA expression and myofiber type composition (indicated by MyHCs mRNA percentage), although MEF2 mRNA in Erhualian was expressed significantly high than in Pietrain (p < 0.05). While in semitendinosus muscle, there was significantly higher PGC-1α, MEF2 mRNA (p < 0.05) in concert with lower MyHC II x (p < 0.05) and II b (p = 0.093) expressed in Erhualian than in Pietrain. Taken together, PGC-1α might have an important role in myofiber type tranformation, but not the crucial factor.