浙贝母精油化学成分GC/MS分析和抑菌活性检测
nalysis of chemical composition by GC/MS and antimicrobial activities of essential oil from Fritillaria thunbergii Miq.
采用水蒸汽蒸馏法提取浙贝母精油，GC/MS分析法结合保留指数分析法鉴定精油化学成分，琼脂扩散法检测精油的抑菌活性。首次鉴定出浙贝母精油的15种化学成分，占精油总离子流色谱峰面积的97.48%，主要成分为正十六酸（53.46%），(E,E)-9,12-十八烷二烯酸甲酯（26.96%）和油酸（9.34%）。浙贝母精油对金黄色葡萄球菌和大肠杆菌均无抑制效果，对白色念珠菌有中等抑制作用。
he essential oil from dried bulbs of Fritillaria thunbergii Miq. obtained by hydrodistillation was analyzed by GC-MS combining with Kovats retention index. The results show that major constituents of this oil were n-Hexadecanoic acid (53.46%), (E, E)-9, 12-Octadecadienoic acid (26.96%) and Oleic Acid (9.34%) and 21 chemical components in the oil were separated and 15 chemical components were identified which represented 97.48% of the total peak. Our result showed that this oil have a moderate antifungal activity against Canidia albicans and no antimicrobial activity to Escherichia coli and Staphylococcus aureus.
曹跃芬、竺锡武、谭琳
药学生物科学研究方法、生物科学研究技术化学工业概论
浙贝母精油GC/MSKovats保留指数抑菌活性
Fritillaria thunbergii Miq.essential oilGC/MSKovats retention indexantimicrobial activity
曹跃芬,竺锡武,谭琳.浙贝母精油化学成分GC/MS分析和抑菌活性检测[EB/OL].(2010-12-24)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/201012-1080.点此复制
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