橙皮素和柚皮素抗癌作用的研究进展

Naringenin and hesperetin, belonging to flavanones and usually occuring as glycosides, are the most abundant flavonoids in citrus fruits. There is a growing concentration on their anti-cancer effects around world recently. Numerous evidences have been shown that the two flavanones attenuate carcinogenesis of environmental pollutants, induce apoptotic cascade in cancer cells, reduce metastatic potential of tumor, and increase efficacy or decrease toxicity of chemotherapy drugs. More healthcare and clinic applications of naringenin and hesperetin are expected based on the broad-spectrum and pleiotropic pharmacologic effects.