长链非编码RNA在心血管疾病中的作用

Background: Long non-coding RNA (lncRNA) is a group of small regulatory RNA, which is more than 200 nucleotides, and does not encode proteins. Research status: A large number of studies showed that lncRNA participate in various physiological and pathological processes. LncRNA can widely involved in these regulation at chromosomes, transcription and post-transcriptional levels. Cardiovascular diseases are serious threat to human health, more and more studies revealed that lncRNA played important roles in cardiovascular diseases. Research purposes: This article will review the definition, origin, characteristics and mechanism of lncRNA and its role in the development of cardiovascular diseases.