生物相容性氧化锌纳米晶的制备初探
n investigation on synthesizing biocompatible ZnO nanocrystals
我们制备了氨丙基三乙氧基硅烷(APTES)修饰的ZnO纳米晶,并研究了它的光学性质和生物毒性。透射电镜(TEM)、动态光散射粒度分析仪(DLS)和X射线衍射(XRD)分析表明,采用溶胶凝胶法我们已经合成了ZnO纳米晶,平均粒径为8 nm。在氙灯330 nm波长激发下,APTES修饰的ZnO纳米晶具有稳定的宽的发光峰,峰位在540-550 nm。细胞活性分析表明,修饰后的ZnO纳米晶对宫颈癌细胞没有明显影响直到其浓度达到20μg/mL。
We have synthesized aminopropyl triethoxysilane (APTES) decorated zinc oxide (ZnO) nanocrystals, and investigated their optical property and cytotoxicity properties. Transmission electron microscopy, dynamic light scattering and X-ray diffraction analysis, demonstrated that crystalline ZnO nanoparticles had been synthesized by using sol-gel method with an average size of 8 nm. The APTES decorated ZnO nanocrystals showed a stable and broad emission band with peak position at around 540-550 nm under excitation of a 330 nm Xe-lamp line. Cell viability analysis indicated that the decorated ZnO nanocrystals had not significant influence on the cervical carcinoma cell proliferation until the concentration was up to of 20μg/mL.)
衡成林、韩宙、杨蓉
生物科学研究方法、生物科学研究技术生物物理学生物化学
氧化锌纳米晶溶胶凝胶法PTES修饰生物相容性
ZnO nanocrystalssol-gel methodAPTES decorationbiocompatibility
衡成林,韩宙,杨蓉.生物相容性氧化锌纳米晶的制备初探[EB/OL].(2015-12-03)[2025-08-04].http://www.paper.edu.cn/releasepaper/content/201512-174.点此复制
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