Mechanosynthesis of a Coamorphous Formulation of Creatine with Citric Acid and Humidity¨CMediated Transformation into a Cocrystal
Mechanosynthesis of a Coamorphous Formulation of Creatine with Citric Acid and Humidity¨CMediated Transformation into a Cocrystal
We report a simple, efficient, and scalable mechanochemical method of preparation of new creatine fitness supplement with increased solubility (compared to the creatine monohydrate) and decreased acidity (compared to creatine hydrochloride).
Jewel Burleson、Jonathan B Lefton、Elfi Kraka、Christina McConville、Tomce Runcevski、Kyle B Pekar、Daniel Sethio
Jewel BurlesonJonathan B LeftonElfi KrakaChristina McConvilleTomce RuncevskiKyle B PekarDaniel Sethio
药学制药化学工业化学
SupplementsCrystal EngineeringCocrystalCoamorphousMechanochemistry
Jewel Burleson,Jonathan B Lefton,Elfi Kraka,Christina McConville,Tomce Runcevski,Kyle B Pekar,Daniel Sethio.Mechanosynthesis of a Coamorphous Formulation of Creatine with Citric Acid and Humidity¨CMediated Transformation into a Cocrystal[EB/OL].(2020-09-29)[2025-05-09].https://chemrxiv.org/engage/chemrxiv/article-details/60c75048bb8c1a85623dbab7.点此复制
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