基于两亲性含氟共聚物刷修饰的抗细菌黏附表面
Bacterial-resistance performance of amphiphilic copolymer brushes consisting of fluorinated polymers and polyacrylamide brush
在本文中，我们以丙烯酰胺(AM)和2-(全氟己基)乙基甲基丙烯酸酯(FMA)为单体，通过表面引发原子转移自由基聚合(SI-ATRP)在硅表面修饰了聚合物刷。通过调节两种单体的比例，制备了一系列不同比例的两亲性聚合物刷修饰的表面。用WCA、XPS、AFM对修饰表面进行了表征。通过SEM和FM观察了内氏放线菌(Actinomyces naeslundii)在修饰表面的粘附，结果证明，当两种单体以3/1 (AM/FMA)的比例聚合时，所得到的共聚物刷修饰表面对内氏放线菌具有最好的抗黏附性。
In this paper, a series of random copolymer brushes of acrylamide (AM) and 2-(perfluorinated hexyl) ethyl methacrylate (FMA) were grafted from initiator-functionalized silicon wafers by surface-initiated atom transfer radical polymerization. WCA, XPS and AFM are used to characterize the modified surfaces. The bacteria attachment assay is performed by SEM and FM. The result obtained in the study shows that the surface modified with amphiphilic polymer brushes has the best resistance to bacteria adhesion, when the mole ratio of AM to FMA is 1/3.
吴海霞、刘传军
生物工程学高分子化合物工业生物科学现状、生物科学发展
高分子化学与物理聚合物刷抗细菌粘附
Polymer Chemistry and PhysicsPolymer BrushResistence of Bacterial Adhesion
吴海霞,刘传军.基于两亲性含氟共聚物刷修饰的抗细菌黏附表面[EB/OL].(2015-11-27)[2025-08-11].http://www.paper.edu.cn/releasepaper/content/201511-729.点此复制
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