不同类型骨科疾患患者D-二聚体与纤维蛋白原检测

Objective To analyze the levels of D-dimer and fibrinogen in plasma of patients with different types of orthopedicdiseases, and to explore the tendency of patients with different types of orthopedic disorders complicated with thromboticdiseases. Methods The measured results of D-dimer, FIB, PT, APTT, TT, WBC and PLT were compared in patients withdifferent types of orthopedic diseases. Results The measured results and rate of abnormality of D-dimer in all groups were thehighest.The second was FIB.From higher to lower in turn for group of femoral fracture, thoracic vertebr and lumbar vertebralfracture, other fracture, cervical vertebra and lumbar disc herniation, the joint disease.Compared with healthy control group,the measured results and rate of abnormality of D-dimer and FIB were significant different. The rate of abnormality of D-dimerin the group of femoral fracture was 100%, thoracic vertebr and lumbar vertebral fracture 94%, other fracture 88.23%, the jointdisease 64.56%, cervical vertebra and lumbar disc herniation 62.63%. Conclusion In addition to fracture and surgery patientswith significant increase in D-dimer, the other types of orthopedic disorders in patients with plasma D-dimer levels and FIBare generally increased.It means that patients with different orthopedic disorders have thrombotic disease tendencies, closeobservation of D-dimer and FIB levels, alert to the occurrence of deep vein thrombosis.