医用纯钛表面微纳复合结构表面的抗菌性能

itanium (Ti) and its alloys have been widely used as implant materials owing to their excellent mechanical properties and biocompatibility. However, they are biologically inert materials. The bacterial-related infection and insufficient osseointegrationof titanium-based materials often occurs clinically after implantationand can lead to implantation failure. Previous studies have shown that compared with pure titanium, a micron-scaled roughness surface is beneficial to osseointegration, because a rough and porous surface structure can enlarge the contact area between the material and cells. However, the micron-scaled surface roughness and the presences of pores can promote the adhesion and proliferation of bacteria, leading to infection. In this study, nano-scaled arrays, fabricated by electrochemical anodization, were performed on a powder-metallurgy-processed micron-scaled surface, and thus, a micron-nano-featured surface was obtained. The results show that the micron-nano featured structure is more hydrophilic and displays a significant antibacterial effect within 8 hours.