Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened
Yuan Meng 1Cottrell Christopher A. 1Voss James 2Ward Andrew B. 1Polveroni Thomas M. 1Ozorowski Gabriel 1Pauthner Matthias 2Messmer Terrence 2McCoy Laura E. 3Andrabi Raiees 2Turner Hannah L. 1Burton Dennis R. 4van Gils Marit J. 5Sanders Rogier W. 6Wilson Ian A. 7Yang Yuhe R.1
作者信息
- 1. Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute
- 2. Department of Immunology and Microbiology, The Scripps Research Institute Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute
- 3. Division of Infection and Immunity, University College London
- 4. Department of Immunology and Microbiology, The Scripps Research Institute Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute||Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University
- 5. Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam
- 6. Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam||Department of Microbiology and Immunology, Weill Medical College of Cornell University
- 7. Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute Scripps Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute||Skaggs Institute for Chemical Biology, The Scripps Research Institute
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Key words
HIV-1/SOSIP/glycan hole/epitope/rabbit immunization/monoclonal antibodies/autologous neutralization引用本文复制引用
Yuan Meng,Cottrell Christopher A.,Voss James,Ward Andrew B.,Polveroni Thomas M.,Ozorowski Gabriel,Pauthner Matthias,Messmer Terrence,McCoy Laura E.,Andrabi Raiees,Turner Hannah L.,Burton Dennis R.,van Gils Marit J.,Sanders Rogier W.,Wilson Ian A.,Yang Yuhe R..Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened[EB/OL].(2025-03-28)[2025-12-13].https://www.biorxiv.org/content/10.1101/827477.学科分类
基础医学/生物科学研究方法、生物科学研究技术/微生物学
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