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首页|基于聚多巴胺敏化的TiO2单晶光电信号放大策略的免疫传感分析

基于聚多巴胺敏化的TiO2单晶光电信号放大策略的免疫传感分析

photoelectron signal amplication strategy based on poly(dopamine)-sensitized TiO2 signal crystal for immunoassay

中文摘要英文摘要

本文设计了一种基于聚多巴胺敏化的有序介孔碳支撑的TiO2单晶的多用途的光电免疫检测方案用于检测肿瘤标记物。聚多巴胺用于增强TiO2单晶的光性能,模拟酶仿生催化剂作为信号放大物质催化苯醌。本文构建了一种通过仿生催化剂标记的前列腺抗原和不同浓度的目标抗原与固定在聚多巴胺敏化的TiO2单晶表面的抗体进行竞争反应的免疫传感器,这为肿瘤标记物的分析提供了一种新的光电化学检测思路。

versatile photoelectrochemical immunoassay protocol based on the poly(dopamine)-sensitized titanium dioxide (TiO2) signal crystal with the support of ordered mesoporous carbon. was designed for quantitative monitoring the tumor markers. Poly(dopamine) was introduced to alter the optical properties of TiO2 signal crystal,enzyme-like biomimetic catalyst was exploited as the signal ampli?er to catalyze the hydroquinone. Herein, a competitive-type immunosensor was fabricated through the biomimetic catalyst labeled prostate speci?c antigen competing with the target antigen of different concentrations to react with the specific antibody anchored on the poly(dopamine)-sensitized TiO2 signal crystal, which provided a new photoelectrochemical consideration for tumor markers analysis.

李宜霖、徐桂芳、陈四红、张书培、张清榕、戴宏、龚玲珊、严惠湘

生物科学现状、生物科学发展生物化学生物物理学光电子技术生物工程学

光电化学聚多巴胺iO2单晶介孔碳

photoelectrochemicalpoly(dopamine)TiO2 signal crystalmesoporous carbon

李宜霖,徐桂芳,陈四红,张书培,张清榕,戴宏,龚玲珊,严惠湘.基于聚多巴胺敏化的TiO2单晶光电信号放大策略的免疫传感分析[EB/OL].(2016-03-09)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201603-87.点此复制

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