离心纺丝及静电纺丝制备的再生丝素纤维的性能对比

Recently, regenerated silk fibroin nanofibers has been applied to biomaterials due to its excellent properties. Electrospinning, as a popular method producing silk fibroin nanofibers, have the limitations of low production rate, high electric fields and selection of the material. In this paper silk fibroin nanofibers with diameter less than 400nm were produced in the centrifugal spinning conditions of 20% concentration and 8000rpm spinneret rotational speed. The surface morphology, secondary structure, thermal properties and orientation of centrifugal-spun silk fibroin fibers and electrospun silk fibroin fibers are contrasted. The result shows that centrifugal-spun fibers have advantage in concentration of β-sheet conformation, crystallinity, thermal stability and orientation, though electrospun fibers have smaller diameter and narrower diameter distribution.