血红蛋白溶液在超滤过程中传质特性的研究

Hemoglobin is the iron-containing oxygen-transport metalloprotein in the red blood cells of vertebrates. Based on the most important function of hemoglobin, most products of blood substitutes in advanced-phase clinical trials are derivatives of hemoglobin. In our research, the relationship among the water permeation flux and the differential operation pressure between outside and inside, the solution concentration in ultrafiltration process was studied by using the way of ultrafiltration. Besides, we also calculated the resistance coefficient from the membrane and the concentration polarization and established a mass transfer model of hemoglobin solution.