基于多级小波域变换的时域扩散荧光层析成像方法

multi-level scheme for time-domain diffuse fluorescence tomography in transmission mode of a slab turbid geometry has been proposed based on discrete wavelet transform, to reach different resolution levels of wavelet domain decomposition and in some degree to reduce the number of unknown parameters at coarse resolution levels and alleviate the ill-posedness of inverse problem. Time-resolved data for experimental validation of the proposed scheme is based on non-contact mode for time-correlated single-photon-counting system. Compared with the traditional algorithm based on the full-spatial domain voxel, experimental results demonstrate that this method could efficiently improve the reconstruction quality and spatial resolution of the reconstructed image, and the quantitativeness is also significantly increased.