2型糖尿病与下肢血管钙化

Background: Vascular calcification in lower limb with diabetes belongs to the arterial calcification，it can be divided into medial calcification and intima calcification. Intima calcification is associated with atherosclerosis. Vascular calcification is one of the characteristics of the development of atherosclerosis .It not only increase the hardness of blood vessels, but also reduce vascular compliance. Moreover, it increases the risk of plaque and vascular rupture and aneurysm formation spontaneously or in angioplasty. It is an important reason for a series of vascular complications such as acute myocardial infarction, vascular avulsion, aortic dissection and ischemic necrosis. Research status: in recent years, with the use of electron beam CT, intravascular ultrasound and DSA, we have found that vascular calcification in lower limb are common in the patients with diabetes, and mainly injure the arteries under the knee. It has been affected with many factors and its pathogenesis still not be fully understood. Research purposes: to study the risk factors and prevent the vascular calcification.