交替惩罚三线性分解二阶校正荧光分析法快速测定牛奶中洛美沙星含量
etermination of Lomefloxacin in Milk Using Alternating Penalty Trilinear Decomposition Algorithm Coupled with Fluorescence Spectroscopy
本文利用交替惩罚三线性分解二阶校正算法结合荧光分析，对有共存药物存在下牛奶中的洛美沙星进行快速分析测定，当三维荧光数据的预估组分数取4时，所得平均回收率达到99.4±1.3%，预测方差均方根（RMSP）为1.16 ng/mL，预测结果良好。实验结果表明，此法可用于多种干扰共存下牛奶中洛美沙星的快速定量测定。
simple method for direct determination of lomfloxacin in milk in the presence of other interferents was described in this paper. It was based on the alternating penalty trilinear decomposition algorithm coupled with fluorescence spectroscopy. When the component number in three-way fluorescent responses was set to 4, the obtained recovery of lomefloxacin in milk was 99.4±1.3%, and the root-mean-square error of prediction(RMSP) was 1.16 ng/mL. The satisfactory result indicated that the proposed method could be applied to simply quantifying lomefloxacin in milk even in the presence of unknown interferences.
江军朵、张卉枫、俞汝勤、朱绍华、夏阿林、刘迪思、吴海龙
药学生物科学研究方法、生物科学研究技术
交替惩罚三线性分解激发-发射荧光牛奶洛美沙星
lomefloxacinalternating penalty trilinear decompositionfluorescence spectroscopymilk
江军朵,张卉枫,俞汝勤,朱绍华,夏阿林,刘迪思,吴海龙.交替惩罚三线性分解二阶校正荧光分析法快速测定牛奶中洛美沙星含量[EB/OL].(2006-11-27)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/200611-749.点此复制
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