六核Cu(Ⅱ)-Ni(Ⅱ)团簇的合成、晶体结构和BSA的结合

he novel hexanuclear {K4H4[Cu4Ni2(μ-O)(μ3-O)4(OAc)8][Cu(OAc)4]} 12H2O (1) cluster has been synthesized from the mixture of Cu(OAc)2 H2O and Ni(OAC)2 4H2O in a potassium acetate buffer solution. The complex was characterized by single crystal X-ray diffraction, elemental analysis, IR spectra and Dynamic light scattering. Crystallographic studies revealed that the molecular core type was M6(μ-O)(μ3-O)4 in 1. Magnetic susceptibility measurements revealed the presence of antiferromagnetic interactions in complex 1. The interaction between the hexanuclear complex with bovine serum albumin (BSA) have been studied by spectroscopies. The results indicated that complex could quench the intrinsic fluorescence of BSA in a static quenching process. ThHexanuclear Cu(Ⅱ)-Ni(Ⅱ) Complexes: Syntheses, crystal structure and BSA protein bindinge binding constants (Kb) and tHexanuclear Cu(Ⅱ)-Ni(Ⅱ) Complexes: Syntheses, crystal structure and BSA protein bindinghe numbers of binding sites (n) obtained are 2.14 × 104 M?1 and 1.01 for complex.