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Estimating the undetected infections in the Covid-19 outbreak by harnessing capture-recapture methods

Estimating the undetected infections in the Covid-19 outbreak by harnessing capture-recapture methods

来源:medRxiv_logomedRxiv
英文摘要

Abstract A major open question, affecting the policy makers decisions, is the estimation of the true size of COVID-19 infections. Most of them are undetected, because of a large number of asymptomatic cases. We provide an efficient, easy to compute and robust lower bound estimator for the number of undetected cases. A “modified” version of the Chao estimator is proposed, based on the cumulative time-series distribution of cases and deaths. Heterogeneity has been accounted for by assuming a geometrical distribution underlying the data generation process. An (approximated) analytical variance formula has been properly derived to compute reliable confidence intervals at 95%. An application to Austrian situation is provided and results from other European Countries are mentioned in the discussion.

B?hning Dankmar、Maruotti Antonello、Rocchetti Irene、Holling Heinz

Southamption Statistical Sciences Research Institute, University of SouthamptonDipartimento di Giurisprudenza, Economia, Politica e Lingue Moderne, Libera Universit¨¤ Ss Maria AssuntaConsiglio Superiore della MagistraturaDepartment of Methods and Statistics, Faculty of Psychology and Sports, University of M¨1nster

10.1101/2020.04.20.20072629

医学研究方法预防医学医药卫生理论

Chao’s lower boundpopulation heterogeneityCOVID-19undetected cases

B?hning Dankmar,Maruotti Antonello,Rocchetti Irene,Holling Heinz.Estimating the undetected infections in the Covid-19 outbreak by harnessing capture-recapture methods[EB/OL].(2025-03-28)[2025-06-18].https://www.medrxiv.org/content/10.1101/2020.04.20.20072629.点此复制

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