双呋喃二氢沉香呋喃醚类衍生物的合成及其杀虫活性
Synthesis and Insecticidal activity of the Ether Analogues of
以苦皮藤(Celastrus angulatus Max.)提取物水解产物中的1β，2β，4α，6α，8β，9α，12-七羟基-β-二氢沉香呋喃为起始原料，与甲磺酰氯（MsCl）反应后，得到一结构新颖的双呋喃二氢沉香呋喃甲磺酸酯（化合物2），并设计合成了8个新的双呋喃二氢沉香呋喃醚类衍生物2.1-2.8，其结构经核磁共振谱、质谱等方法鉴定。初步的杀虫活性测定结果表明：化合物2.1-2.8对三龄粘虫具有较强的胃毒活性，其中烯丙基醚和正丁基醚衍生物（2.5和2.6）在20mg•mL-1的浓度下对粘虫3龄幼虫的死亡率分别为66.7%和50.0%。
he structure of 1β,2β,4α,6α,8β,9α,12-hepthydroxy-β-dihydroagarofuran was simplified to be 1β,4α,6α,9α-tetrahydroxy-8β-methylsulfony-2β,12-ether-β-dihydroagarofuran and eight new dihyd- roagarofuran ether analogues were synthesized based on 1β,4α,6α,9α-tetrahydroxy-8β-methylsulfony-2β,12-ether-β-dihydroagarofuran as staring materials.The structures of the compounds were elucidated mainly based on NMR and MS spectral data. Bioassay Results showed that they exhibited some degree stomach toxicity against the third instar larvae of Mythimna separata at the concentration of 20mg•mL-1.
吴文君、张继文、石新卫、郑绍军、李圣坤
植物保护农药工业昆虫学
β-二氢沉香呋喃结构修饰醚类衍生物杀虫活性
β-dihydroagarofuranstructure modificationinsecticidal activity
吴文君,张继文,石新卫,郑绍军,李圣坤.双呋喃二氢沉香呋喃醚类衍生物的合成及其杀虫活性[EB/OL].(2008-04-28)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/200804-970.点此复制
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