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藕节促凝血有效组分的筛选及其凝血作用的研究

Study on the Screening and Coagulant Activity of the Effective Procoagulant Components in Nodus Nelumbinis Rhizomatis

中文摘要英文摘要

目的:筛选藕节促凝血的有效组分。方法:采用毛细管法测定小鼠凝血时间(CT);采用剪尾法测定小鼠出血时间(BT);采用试管法测定小鼠活化部分凝血活酶时间(APTT)和凝血酶原时间(PT)。结果:藕节提取物组分Ⅰ和组分Ⅱ均表现出较好的促凝血作用,组分Ⅲ没有活性。结论:藕节促凝血的有效组分为组分Ⅰ和组分Ⅱ。

Objective: To screen the effective procoagulant components in nodus nelumbinis rhizomatis. Method:Coagulation time(CT)was tested by capillary method in mice.Bleeding time(BT)was determined by cutting-tail method in mice. Activated partial thromboplastin time (APTT)and prothrombin time(PT)were evaluated by test tube method in mice. Result: ComponentⅠand componentⅡ of nodus nelumbinis rhizomatis behave procoagulant function,and componentⅢ does not behave the activity of procoagulant. Conclusion: The effective procoagulant components in nodus nelumbinis rhizomatis are componentⅠ and componentⅡ.

周新华、曲筱静、夏文水、张家骊

药学中医学基础医学

藕节组分促凝血

Nodus nelumbinis rhizomatisomponentProcoagulant

周新华,曲筱静,夏文水,张家骊.藕节促凝血有效组分的筛选及其凝血作用的研究[EB/OL].(2008-03-25)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/200803-738.点此复制

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