E2-Ang(1-7)-Mas轴的下游信号通路
ownstream signaling of ACE-Ang(1-7)-Mas axis
背景:ACE2-Ang(1-7)-Mas轴具有拮抗ACE-AngⅡ-AT1R经典轴的作用,参与体内众多的生理反应,在循环、泌尿、消化等系统及炎症反应中发挥着重要的保护作用。研究现状:ACE2-Ang(1-7)-Mas轴功能的发挥与其信号通路密切相关。研究用途:探讨此调节轴的生物学功能及其信号传导通路将为相关疾病的治疗提供新的思路。
E2-Ang(1-7)-Mas axis antagonistics ACE-AngⅡ-AT1R classic axis in many physiological responses in vivo,which plays an important protective role in circulation ,urinary,digestive systerms and inflammation response. The biological functions of ACE2-Ang(1-7)-Mas axis is closely related to its signaling pathways. Exploring the biological function of this adjustment axis and its signaling transduction pathways will provide new ideas for related diseases.
崔立建、刘瑞霞、阴赪宏
基础医学生理学分子生物学
E2-Ang(1-7)-Mas轴生物学功能信号通路
E2-Ang(1-7)-Mas axisbiological functionsignaling pathway
崔立建,刘瑞霞,阴赪宏.E2-Ang(1-7)-Mas轴的下游信号通路[EB/OL].(2014-02-20)[2025-05-01].http://www.paper.edu.cn/releasepaper/content/201402-342.点此复制
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