不同支持模式下体外膜氧合期间血小板变化的回顾性队列研究

Objective Retrospective analysis of platelet count changes in adults during different ECMO support. Methods 40 adult patients who received ECMO support in Gaozhou People's Hospital from January 2019 to October 2021 were retrospectively enrolled in the study. According to application scenarios, they were divided into ECMO support group after cardiac surgery (surgery group, n=17) and ECMO support group without cardiac surgery (non-surgery group, n=23). Results The changes of platelet count in the two groups showed a curve and dual-time pattern, which began to decline 2-3 days after the initiation of ECMO and reached the bottom 3-4 days later, and then the platelet curve rose and showed different prognostic curve changes, that is, the survival group had a relatively higher platelet value and a more stable value rise curve than the death group. The mean platelet transfusion volume of all patients was (1.602.00) units, and nearly 60% (59.09%) patients achieved effective platelet elevation after the first infusion. Conclusion The platelet changes supported by ECMO showed a curve and dual time pattern, and usually reached the lowest value on the 3rd to 4th day. The prognosis of patients was correlated with platelet rebound.