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高脂血症与肺损伤

Hyperlipidemia and pulmonary injury

中文摘要英文摘要

高脂血症已经不再被单纯看作心脑血管的病理基础,其对机体各器官组织所致的损伤及所引起的复杂并发症越来越受到人们的重视。高脂血症不仅可以导致心血管系统、肝、肾等脏器的病变,也可导致肺动脉粥样硬化、间质性肺炎、肺胆固醇性肉芽肿样改变、肺重构等病变。这些病变长期继续发展下去,有导致或加速其它各种严重病变的风险,如肺动脉高压、肺纤维和右心室肥大等合并症。 本文对高脂血症所致的肺损伤进行了概括,并对其可能的损伤机制进行了总结。

Hyperlipidemia is no longer simply seen as the pathological basis of cardiovascular, increasing attention has been paid to its various organs and tissues injuries and other complex complications. Hyperlipidemia can not only lead to disease of the cardiovascular system, liver, kidney and other organs or tissues, but also can lead to pulmonary artery atherosclerosis, interstitial pneumonia, lung cholesterol granuloma-like change, reconstruction and other lung diseases. These diseases continue to develop long-termly, may cause or accelerate the risk of other various serious diseases or complications, such as pulmonary hypertension, pulmonary fibrosis and right ventricular hypertrophy. In this paper, we summarized lung injuries induced by hyperlipidemia and the possible mechanism of injury.

常猇宇、李会恩、周建红、杨奎

基础医学内科学

高脂血症肺损伤机制

Hyperlipidemialung injurymechanism of injury

常猇宇,李会恩,周建红,杨奎.高脂血症与肺损伤[EB/OL].(2010-05-26)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/201005-655.点此复制

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