再生丝素蛋白/P(LLA-CL)共混超细纤维膜的制备及性能研究
Preparation and Properties of Regenerated Silk Fibroin/ P(LLA-CL) Blend Ultra-fine Fibrous Membrane
通过静电纺丝法制备了再生丝素蛋白/P(LLA-CL)共混超细纤维膜。用场发射扫描电镜（FE-SEM）、傅立叶红外光谱分析仪（FT-IR）、热重分析仪（TGA）、多功能拉伸仪以及MTT法对共混纤维多孔膜的形貌、分子结构、热性能、力学性能及生物相容性进行测试。结果表明：共混超细纤维膜中随P(LLA-CL)的加入纤维直径变粗，均匀性变差；P(LLA-CL)的混入可以使SF的二级结构从无规向有序转变，且可以有效提高SF的热性能以及力学性能，但共混比为50/50时会出项相分离情况；而SF/ P(LLA-CL)共混膜对细胞的粘附和增殖都较为有利。
P(LLA-CL)/silk fibroin blend ultra-fine fibrous membrane was fabricated by electrospinning. The morphology, molecule structure, thermal performance, mechanical properties and biocompatibility of P(LLA-CL) /SF blend membrane were investigated by FE-SEM, FT-IR, TGA, Multi-Purpose Tensile Tester and MTT assay. The results show that the fiber diameters are increased and the uniformity tend to be worse with the increase of P(LLA-CL).The secondary structures are changed from random coil into ordered structure by blending P(LLA-CL).What's more, the thermal performance and mechanical properties could be improved by adding P(LLA-CL).However, the fibrous membrane of weight ratio of 50/50 is found phase separation. P(LLA-CL)/silk fibroin blend ultra-fine fibrous membrane is good for cell adhesion and proliferation.
雷白鸽、边瑞琦、谢军军、熊杰、樊晓娜
材料科学生物科学研究方法、生物科学研究技术生物工程学
复合材料P(LLA-CL)再生丝素蛋白静电纺丝共混超细纤维膜
omposite materialsP(LLA-CL)regenerated silk fibroinelectrospinningblend ultra-fine fibrous membrane
雷白鸽,边瑞琦,谢军军,熊杰,樊晓娜.再生丝素蛋白/P(LLA-CL)共混超细纤维膜的制备及性能研究[EB/OL].(2011-07-25)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201107-355.点此复制
评论