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寿胎丸对复发性流产小鼠蜕膜蛋白质差异表达分析

he analysis of Shoutaiwan on the differential expression of decidual protein in recurrent abortion mice

中文摘要英文摘要

分析寿胎丸对复发性流产小鼠蜕膜蛋白质组的影响。方法:建立复发性流产模型,应用蛋白质组学技术分析寿胎丸对复发性流产小鼠蜕膜蛋白质差异表达。结果:发现并鉴定了30个可能与复发性流产及寿胎丸干预相关的蛋白质。结论:提示复发性流产是一多种蛋白质参与的复杂过程,小鼠蜕膜组织的比较蛋白质组学分析是筛选复发性流产病变相关蛋白质的可靠方法之一;寿胎丸可调节复发性流产小鼠蜕膜组织多种蛋白质的表达。

IABSTRACT]Objective:To analysis the effective mechanisms of recurrent abortion mice decidual protein group with Shoutaiwan.Method:The preparation of recurrent abortion models, The application of proteomics technology to analysis protein differential expression of recurrent abortion in mice decidua with Shoutaiwan.Result:30 differential expression protein spots which maybe related to recurrent abortion and Shoutaiwan intervention were found. and identified.Conclusion: It indicated that recurrent abortion is a complicated process refer to diverse proteins participate, the comparison proteome analysis of mice decidual tissue was a reliable method to sieve related proteins pots for recurrent abortion pathological changes. Shoutaiwan may regulate the expression of various proteins of recurrent abortion decidual tissue of mice.

雷磊、李慧芳、谭展望

中医学医学研究方法基础医学

寿胎丸复发性流产蜕膜蛋白质组学双向凝胶电泳质谱

words:ShoutaiwanRecurrent abortionDeciduaProteomicsTwo-dimensional electrophoresisMass spectrometry

雷磊,李慧芳,谭展望.寿胎丸对复发性流产小鼠蜕膜蛋白质差异表达分析[EB/OL].(2012-08-27)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201208-202.点此复制

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