Psychological morbidities and fatigue in patients with confirmed COVID-19 during disease outbreak: prevalence and associated biopsychosocial risk factors
Psychological morbidities and fatigue in patients with confirmed COVID-19 during disease outbreak: prevalence and associated biopsychosocial risk factors
Abstract ObjectiveThe coronavirus disease 2019 (COVID-19) – a novel and highly infectious pneumonia – has now spread across China and beyond for over four months. However, its psychological impact on patients is unclear. We aim to examine the prevalence and associated risk factors for psychological morbidities and fatigue in patients with confirmed COVID-19 infection. MethodsAmidst the disease outbreak, 41 out of 105 COVID-19 patients in a local designated hospital in China were successfully assessed using a constellation of psychometric questionnaires to determine their psychological morbidities and fatigue. Several potential biopsychosocial risk factors (including pre-existing disabilities, CT severity score of pneumonia, social support, coping strategies) were assessed through multivariable logistic regression analyses to clarify their association with mental health in patients. Results43.9% of 41 patients presented with impaired general mental health, 12.2% had post-traumatic stress disorder (PTSD) symptoms, 26.8% had anxiety and/or depression symptoms, and 53.6% had fatigue. We did not find any association between pneumonia severity and psychological morbidities or fatigue in COVID-19 patients. However, high perceived stigmatization was associated with an increased risk of impaired general mental health and high perceived social support was associated with decreased risk. Besides, negative coping inclination was associated with an increased risk of PTSD symptoms; high perceived social support was associated with a decreased risk of anxiety and/or depression symptoms. ConclusionsPsychological morbidities and chronic fatigue are common among COVID-19 patients. Negative coping inclination and being stigmatized are primary risk factors while perceived social support is the main protective factor.
Xia Fei、Li Lingjiang、Jiang Xiangao、Lu Guang Ming、Chen Wei、Qi Rongfeng、Liu Saiduo、Luo Song、Sun Zhi Yuan、Surento Wesley、Zhou Chang Sheng、Thompson Paul M.、Zhang Long Jiang、Cheng Fang、Hong Ailing
Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing UniversityMental Health Institute of the Second Xiangya Hospital, Central South University, China National Clinical Research Center for Mental Health Disorders, National Technology Institute of PsychiatryDepartments of Infectious Disease, Wenzhou Central HospitalDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing UniversityDepartment of Radiology, Jinling Hospital, Southern Medical University||Department of Radiology, The Second Affiliated Hospital and Yuying Children?ˉs Hospital of Wenzhou Medical UniversityDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing University||Department of Radiology, Jinling Hospital, Southern Medical UniversityDepartments of Infectious Disease, Wenzhou Central HospitalDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing UniversityDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing UniversityImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern CaliforniaDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing UniversityImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern CaliforniaDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing UniversityDepartments of Infectious Disease, Wenzhou Central HospitalDepartments of Infectious Disease, Wenzhou Central Hospital
医药卫生理论医学研究方法神经病学、精神病学
coronavirus disease 2019mental morbiditiesfatiguepost-traumatic stress disorder symptomstigmatizationsocial support
Xia Fei,Li Lingjiang,Jiang Xiangao,Lu Guang Ming,Chen Wei,Qi Rongfeng,Liu Saiduo,Luo Song,Sun Zhi Yuan,Surento Wesley,Zhou Chang Sheng,Thompson Paul M.,Zhang Long Jiang,Cheng Fang,Hong Ailing.Psychological morbidities and fatigue in patients with confirmed COVID-19 during disease outbreak: prevalence and associated biopsychosocial risk factors[EB/OL].(2025-03-28)[2025-05-22].https://www.medrxiv.org/content/10.1101/2020.05.08.20031666.点此复制
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