兔腹主动脉瘤与人腹主动脉瘤比较分析

o compare the difference of abdominal aortic aneurysm (AAA) between rabbit and human. The New Zealand rabbits underwent the perfusion of the abdominal aorta respectively with porcine pancreatic elastase. The AAA morphologic, hemodynamics and pathological changes were investigated and compared between rabbits and humans. Ten AAA of rabbits were analyzed within one year. AAA was successfully identified by ultrasound on postprocedural 4 week. The ratio of aortic diameter and length of rabbit AAA were not significant changed. There were not found the parietalthrombus and the twist of aneurysm neck and body. The turbulent flow was identified in the aneurysm body. The peak systolic velocity of inflow tract was significant higher than one of aneurysm body. The pathological changes were showed as inflammatory cell infiltration of the aortic wall and loss of elastic tissue. The rabbit model of AAA is similar to human, and this model is suitable for hemodynamics and treatment research about human AAA.