液晶生物传感器研究进展

Liquid crystals (LCs) are special materials which present with a special state intermediate between solid phase and liquid phase.A key to making LCs well-suited as sensing element is that LCs can respond rapidly to chemical and biomolecular binding events, and can transform them into amplified and visible optical appearances. These property make LCs of great potential for providing a visual and label-free biosensor that well suited the primary screening assay of analytes without the requirement of complex instruments. Typical liquid crystal biosensor mainly depends on the special birefringence phenomenon and the orientation of liquid crystal molecules which are extremely sensitive to the changes of surface modification. Based biomolecular recognitions or catalytic reactions , LCs biosensors have been developed for the detection of antigen-antibody, proteins, nucleic acids, enzymes and so on.